Real World Example

A CellProfiler Approach to Analyzing Tissue Data

Kyle Karhohs

Imaging tissue slices provides a wealth of data about the spatial composition and number of the various cell types that make up a tissue. Interactions among cells within a tissue are crucial to understanding the role of the inflammation that is triggered by the invasion of cancerous cells. The strength of the inflammatory response has been linked to the prognosis of certain cancers such as lymphoma.

Quantifying the spatial relationship among cells in the crowded environment of a tissue requires reliable segmentation...

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